Cerebral oedema with coning in diabetic keto-acidosis. Report of 2 survivors

S Afr Med J. 1991 Jun 15;79(12):727-31.


Two children presented with a first episode of diabetic ketoacidosis. Initially both patients made a good clinical and biochemical recovery, but suddenly developed neurological signs consistent with a diagnosis of tentorial herniation. Cranial computed tomography showed signs of cerebral oedema in both cases with evidence of uncal and tentorial herniation in 1 patient, which resolved after the appropriate treatment. The excellent neurological outcome emphasises the need for early recognition and treatment of sudden onset brain oedema in diabetic keto-acidosis.

Publication types

  • Case Reports

MeSH terms

  • Brain / diagnostic imaging
  • Brain Edema / diagnostic imaging
  • Brain Edema / etiology*
  • Child
  • Diabetic Ketoacidosis / complications*
  • Female
  • Humans
  • Tomography, X-Ray Computed