Review of laser speckle contrast techniques for visualizing tissue perfusion

Lasers Med Sci. 2009 Jul;24(4):639-51. doi: 10.1007/s10103-008-0626-3. Epub 2008 Dec 3.

Abstract

When a diffuse object is illuminated with coherent laser light, the backscattered light will form an interference pattern on the detector. This pattern of bright and dark areas is called a speckle pattern. When there is movement in the object, the speckle pattern will change over time. Laser speckle contrast techniques use this change in speckle pattern to visualize tissue perfusion. We present and review the contribution of laser speckle contrast techniques to the field of perfusion visualization and discuss the development of the techniques.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Humans
  • Laser-Doppler Flowmetry
  • Lasers*
  • Pattern Recognition, Automated / methods
  • Pattern Recognition, Automated / statistics & numerical data
  • Photography
  • Regional Blood Flow
  • Scattering, Radiation
  • Skin / blood supply