[Familial summer-type hypersensitivity pneumonitis in a husband and wife]

Arerugi. 2008 Nov;57(11):1182-7.
[Article in Japanese]

Abstract

We encountered a family in which two of four members, the husband and his wife, had summer-type hypersensitivity pneumonitis at the same time, about two months after they moved to the residence. A 45-year-old man had cough, fever and exertional dyspnea. Chest computed tomography showed diffuse centriloblar ground-glass attenuation in both lung fields. His 43-year-old wife had chest small nodular shadows and similar symptoms to his husband. Serum anti-Tricosporon cutaneum (T. asahi: serotype II and T. mucoides: serotype I) antibodies of both patients were at the positive level. They were given diagnosis as summer-type hypersensitivity pneumonitis by radiological, serological and histological examinations. The symptoms in both cases were improved immediately after administration of systemic corticosteroid. Summer-type hypersensitivity pneumonitis was assumed to be caused for about two months duration of expousure to antigen.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Adult
  • Alveolitis, Extrinsic Allergic / diagnosis*
  • Alveolitis, Extrinsic Allergic / drug therapy
  • Alveolitis, Extrinsic Allergic / etiology*
  • Antibodies, Fungal / blood
  • Antigens, Fungal / adverse effects
  • Biomarkers / blood
  • Environmental Exposure / adverse effects
  • Female
  • Humans
  • Lung / pathology
  • Male
  • Middle Aged
  • Spouses*
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Trichosporon / immunology
  • Trichosporon / pathogenicity

Substances

  • Adrenal Cortex Hormones
  • Antibodies, Fungal
  • Antigens, Fungal
  • Biomarkers