Influence of bioengineered skin substitutes on diabetic foot ulcer and venous leg ulcer outcomes

C Barber; A Watt; C Pham; K Humphreys; A Penington; K Mutimer; M Edwards; G Maddern

doi:10.12968/jowc.2008.17.12.31766

Influence of bioengineered skin substitutes on diabetic foot ulcer and venous leg ulcer outcomes

J Wound Care. 2008 Dec;17(12):517-27. doi: 10.12968/jowc.2008.17.12.31766.

Authors

C Barber¹, A Watt, C Pham, K Humphreys, A Penington, K Mutimer, M Edwards, G Maddern

Affiliation

¹ ASERNIP-S, Royal Australasian College of Surgeons, Stepney, Australia.

PMID: 19052516
DOI: 10.12968/jowc.2008.17.12.31766

Abstract

This systematic review indicates that bioengineered skin substitutes with a dermal component may improve healing outcomes in diabetic foot ulcers and venous leg ulcers. However, better designed trials with longer follow-up periods are needed.

Publication types

Research Support, Non-U.S. Gov't
Review
Systematic Review

MeSH terms

Cell Culture Techniques
Chronic Disease
Coated Materials, Biocompatible / therapeutic use
Collagen / therapeutic use
Diabetic Foot / therapy*
Health Services Needs and Demand
Humans
Randomized Controlled Trials as Topic
Research Design
Safety
Skin Transplantation
Skin, Artificial* / standards
Skin, Artificial* / supply & distribution
Treatment Outcome
Varicose Ulcer / therapy*
Wound Healing

Substances

Apligraf
Biobrane
Coated Materials, Biocompatible
TransCyte
Collagen