Suppression of human immunodeficiency virus type 1 viral load during acute measles

Pediatr Infect Dis J. 2009 Jan;28(1):63-5. doi: 10.1097/INF.0b013e318184eed2.

Abstract

Acute measles virus infection can result in a transient decrease in plasma human immunodeficiency virus type 1 (HIV-1) RNA loads. We report the kinetics of plasma HIV-1 RNA loads in 2 Zambian children with confirmed and probable measles, and show that the decline in viral load is of similar magnitude to the first-phase decay rate after initiation of antiretroviral therapy.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Female
  • HIV Infections / immunology
  • HIV Infections / virology*
  • HIV-1 / genetics
  • HIV-1 / growth & development*
  • Humans
  • Infant
  • Measles / immunology
  • Measles / virology*
  • Measles Vaccine / administration & dosage
  • Measles Vaccine / immunology
  • Measles virus / growth & development*
  • Measles virus / immunology
  • RNA, Viral / blood
  • Reverse Transcriptase Polymerase Chain Reaction
  • Viral Load
  • Zambia

Substances

  • Measles Vaccine
  • RNA, Viral