Cryptococcus neoformans septicemia in an immunocompetent neonate: first case report in Thailand

Narongsak Nakwan; Sopapan Ngerncham; Pimol Srisuparp; Keswadee Lapphra; Kulkanya Chokephaibulkit

Cryptococcus neoformans septicemia in an immunocompetent neonate: first case report in Thailand

Southeast Asian J Trop Med Public Health. 2008 Jul;39(4):697-700.

Authors

Narongsak Nakwan¹, Sopapan Ngerncham, Pimol Srisuparp, Keswadee Lapphra, Kulkanya Chokephaibulkit

Affiliation

¹ Division of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Pran Nok Road, Bangkok 10700, Thailand.

PMID: 19058608

Abstract

Neonatal infection due to Cryptococcus neoformans is extremely rare. We report a case of a 21-day-old neonate diagnosed with cryptococcal septicemia who was successfully treated with amphotericin B. He was born to a human immunodeficiency virus (HIV) seronegative mother. This report alerts general pediatricians and neonatologists to consider Cryptococcus neoformans infection as a possible cause of sepsis in newborn infants.

Publication types

Case Reports

MeSH terms

Amphotericin B / administration & dosage*
Antifungal Agents / administration & dosage*
Cryptococcosis / diagnosis*
Cryptococcosis / drug therapy*
Cryptococcosis / immunology
Cryptococcosis / microbiology
Cryptococcus neoformans / isolation & purification
Humans
Immunocompetence
Infant, Newborn
Male
Sepsis / drug therapy*
Sepsis / immunology
Sepsis / microbiology*

Substances

Antifungal Agents
Amphotericin B