Anterior lamellar keratoplasty over penetrating keratoplasty for optical, therapeutic, and tectonic indications: a case series

Am J Ophthalmol. 2009 Apr;147(4):697-702.e2. doi: 10.1016/j.ajo.2008.10.002. Epub 2008 Dec 5.

Abstract

Purpose: To report a consecutive case series of patients who underwent anterior lamellar keratoplasty (ALK) over a preexisting penetrating keratoplasty (PK).

Design: Retrospective, interventional case series.

Methods: Eight patients (8 eyes) were identified from the Singapore Corneal Transplant Study database, in a single institution (Singapore National Eye Center) from patients who underwent ALK performed over a PK. Main outcome measures were final visual acuity (VA), graft failure (ALK, PK or both), successful restoration of tectonic integrity in tectonic indications, and eradication of infection in therapeutic cases.

Results: The indications for surgery were therapeutic in 3 patients, optical in 3 patients, and tectonic in 2 patients. Postoperatively the best-corrected visual acuity (BCVA) improved in 5 eyes and remained unchanged in 3 eyes. Mean VA improved significantly after ALK; the mean preoperative BCVA was 1.52 +/- 0.25 and the mean postoperative BCVA was 0.87 +/- 0.26 (P = .032). Three of the 8 eyes post-lamellar keratoplasty (LK) managed to attain a BCVA equal to post-PK BCVA. Two patients had suture micro-perforations while 1 patient required a repeat ALK for recurrence of infection.

Conclusion: ALK may be a considered as a viable alternative to a repeat PK for a variety of optical, therapeutic, and tectonic indications.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Corneal Diseases / physiopathology
  • Corneal Diseases / surgery*
  • Corneal Transplantation / methods*
  • Female
  • Humans
  • Intraoperative Complications
  • Keratoplasty, Penetrating*
  • Male
  • Middle Aged
  • Postoperative Complications
  • Retrospective Studies
  • Treatment Outcome
  • Vision Disorders / physiopathology
  • Vision Disorders / rehabilitation
  • Visual Acuity / physiology