Control of gluconate utilization in Sinorhizobium meliloti

J Bacteriol. 2009 Feb;191(4):1355-8. doi: 10.1128/JB.01317-08. Epub 2008 Dec 5.


The Sinorhizobium meliloti megaplasmid pSymA has previously been implicated in gluconate utilization. We report a locus on pSymA encoding a putative tripartite ATP-independent periplasmic (TRAP) transporter that is required for gluconate utilization. The expression of this locus is negatively regulated by a GntR family regulator encoded adjacent to the transporter operon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Endopeptidases / genetics
  • Endopeptidases / metabolism
  • Gene Expression Regulation, Bacterial / physiology
  • Gluconates / metabolism*
  • Mutation
  • Plasmids / chemistry
  • Plasmids / genetics*
  • Sinorhizobium meliloti / genetics
  • Sinorhizobium meliloti / metabolism*


  • Gluconates
  • Endopeptidases
  • Bacillus polymyxa proteinase
  • gluconic acid