Contributions of the basal ganglia and functionally related brain structures to motor learning

Behav Brain Res. 2009 Apr 12;199(1):61-75. doi: 10.1016/j.bbr.2008.11.012. Epub 2008 Nov 17.


This review discusses the cerebral plasticity, and the role of the cortico-striatal system in particular, observed as one is learning or planning to execute a newly learned motor behavior up to when the skill is consolidated or has become highly automatized. A special emphasis is given to imaging work describing the neural substrate mediating motor sequence learning and motor adaptation paradigms. These results are then put into a plausible neurobiological model of motor skill learning, which proposes an integrated view of the brain plasticity mediating this form of memory at different stages of the acquisition process.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adaptation, Psychological / physiology*
  • Animals
  • Basal Ganglia / anatomy & histology*
  • Basal Ganglia / physiology*
  • Cerebral Cortex / anatomy & histology
  • Cerebral Cortex / physiology
  • Humans
  • Memory / physiology*
  • Motor Skills / physiology*
  • Neuronal Plasticity / physiology*