Spinal-cord MRI in multiple sclerosis: conventional and nonconventional MR techniques

Neuroimaging Clin N Am. 2009 Feb;19(1):81-99. doi: 10.1016/j.nic.2008.09.005.


Multiple sclerosis is a diffuse disease of the central nervous system, and MRI of the spinal cord is highly recommended in the clinical evaluation of patients suspected of having multiple sclerosis. Within the new diagnostic criteria, spinal cord MRI increases sensitivity and possibly specificity for MS, but further work is needed to investigate other criteria that may give greater weight to the presence of cord lesions in patients with clinically isolated syndromes or suspected relapsing-remitting multiple sclerosis. Techniques should be further studied and validated in studies comparing these techniques with clinical status and histopathology, however.

Publication types

  • Review

MeSH terms

  • Diffusion Magnetic Resonance Imaging / methods
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / trends
  • Magnetic Resonance Spectroscopy / methods
  • Multiple Sclerosis / diagnosis*
  • Spinal Cord / pathology*