Bias, Spin, and Misreporting: Time for Full Access to Trial Protocols and Results

PLoS Med. 2008 Nov 25;5(11):e230. doi: 10.1371/journal.pmed.0050230.

Abstract

An-Wen Chan discusses the implications of a new study inPLoS Medicine that suggests that the randomized trial literature is skewed towards reporting favorable results.

MeSH terms

  • Bias
  • Drug Approval / statistics & numerical data*
  • Humans
  • Mandatory Reporting*
  • Publication Bias*
  • Randomized Controlled Trials as Topic / statistics & numerical data*
  • United States
  • United States Food and Drug Administration*