The Iranian Ministry of Health documented that about 1500 people died from drowning annually in Iran between years 2000 and 2001. This study is a descriptive, retrospective, population-based analysis of 342 unintentional drowning deaths occurring to residents and tourists in Guilan and Mazandran Provinces in Iran over a 1-year period (2005-2006), using multiple data sources. The findings from this study demonstrate that the drowning rate for residents of the study population, 4.24 per 100,000, is much higher than drowning rates for populations in developed economies in Europe. Risk factors for drowning in the study populations include male gender, young age, and swimming in unsupervised areas. Drownings occurred most frequently in rivers, followed by canals and lakes. While much more remains to be done to investigate the problems associated with drowning deaths and injuries in Iran, the information obtained from this study can help point the way to targeted interventions.