Sarcoidosis: a rare cause of Kleine-Levine-Critchley syndrome

Sarcoidosis Vasc Diffuse Lung Dis. 2008 Sep;25(1):60-3.

Abstract

Hypothalamic sarcoidosis is a rare entity that can alter the hypothalamic-pituitary axis and induce various combinations of endocrine changes. We present a case of neurosarcoidosis with uncommon features of hypersomnolense and hyperphagia. Current strategies to increase awareness and prevention of the harmful effects of obesity require clinicians to be cognizant of potential disorders that produce these features The mechanism, differential diagnosis and therapeutic options of this organic etiology are reviewed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Azathioprine / therapeutic use
  • Biopsy
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Follow-Up Studies
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Kleine-Levin Syndrome / diagnosis
  • Kleine-Levin Syndrome / drug therapy
  • Kleine-Levin Syndrome / etiology*
  • Lymph Nodes / pathology
  • Magnetic Resonance Imaging
  • Male
  • Mediastinum
  • Prednisone / therapeutic use
  • Sarcoidosis / complications*
  • Sarcoidosis / diagnosis
  • Sarcoidosis / drug therapy

Substances

  • Glucocorticoids
  • Immunosuppressive Agents
  • Azathioprine
  • Prednisone