Prepregnancy body mass index, gestational weight gain, and risk of hypertensive pregnancy among Latina women

Am J Obstet Gynecol. 2009 Feb;200(2):167.e1-7. doi: 10.1016/j.ajog.2008.08.021. Epub 2008 Dec 13.

Abstract

Objective: Prepregnancy body mass index (BMI) and gestational weight gain have been associated with hypertensive disorders of pregnancy, but previous studies have included few Latinas, a group at increased risk.

Study design: We examined these associations in the Latina Gestational Diabetes Mellitus Study, a prospective cohort of 1231 women conducted from 2000 to 2004.

Results: In multivariable analysis, obese women (BMI > 29.0 kg/m(2)) had 2.5 times the risk of hypertensive pregnancy (95% confidence interval [CI], 1.3-4.8) and 2.7 times the risk of preeclampsia (95% CI, 1.2-5.8), compared with women whose BMI was 19.8 to 26.0 kg/m(2). Women with excessive gestational weight gain had a 3-fold increased risk of a hypertensive disorder of pregnancy (95% CI, 1.1-7.2) and a 4-fold risk of preeclampsia (95% CI, 1.2-14.5), compared with women achieving weight gain guidelines.

Conclusion: These findings suggest prepregnancy obesity and excessive weight gain are associated with hypertension in pregnancy in a Latina population and could be potentially modifiable risk factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Body Mass Index
  • Cohort Studies
  • Female
  • Hispanic Americans
  • Humans
  • Hypertension, Pregnancy-Induced / etiology*
  • Obesity / complications*
  • Pregnancy
  • Puerto Rico / ethnology
  • Risk Factors
  • Weight Gain
  • Young Adult