Endiandric Acid Analogues from the Roots of Beilschmiedia erythrophloia
- PMID: 19072217
- DOI: 10.1021/np800504w
Endiandric Acid Analogues from the Roots of Beilschmiedia erythrophloia
Abstract
Investigation of the roots of Beilschmiedia erythrophloia has led to the isolation of seven new endiandric acid analogues, erythrophloins A-F (1-6) and beilcyclone A (7), together with 11 known compounds. The structures of 1-7 were determined using spectroscopic techniques. Two constituents, erythrophloin C (3) and suberosol B (8), exhibited antitubercular activity against Mycobacterium tuberculosis H37Rv, showing MIC values of 50 and 28.9 microg/mL, respectively.
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