Applying mouse complex-trait resources to behavioural genetics

Nature. 2008 Dec 11;456(7223):724-7. doi: 10.1038/nature07630.

Abstract

Studies of the genetic basis of behaviour in mice are at a turning point. Soon, new resources will enable the behavioural function of all genes to be tested and the networks of genes, messenger RNAs and proteins involved in a particular behaviour to be identified. Using these resources, scientists will be able to analyse mouse behaviour at an unprecedented level of detail. Interpreting the new data, however, will require a shift in focus from gene-based approaches to network-based approaches.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Behavior, Animal / physiology*
  • Computational Biology
  • Genetics, Behavioral / methods*
  • Mice
  • Mice, Knockout
  • Mutagenesis
  • Phenotype