Effect of cost on the self-administration and efficacy of nicotine gum: a preliminary study

Prev Med. 1991 Jul;20(4):486-96. doi: 10.1016/0091-7435(91)90046-7.


METHODS. One hundred six smokers seen in a family practice received brief physician advice and a prescription for nicotine gum. Smokers were randomly assigned to pay $20, $6, or $0/box of nicotine gum and followed for 6 months. RESULTS. Decreased cost increased the incidence of obtaining gum, the amount of gum used, and the incidence of long-term use (P less than 0.05). Decreased cost also increased cessation attempts and 1-week cessation (P less than 0.05) and appeared to increase abstinence at 6-month follow-up (19% vs 6% vs 8%, P less than 0.10). Cost-benefit estimates suggest that an insurance plan, HMO, etc., would recoup any costs in subsidizing nicotine gum and perhaps incur a net financial gain.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Chewing Gum*
  • Cost-Benefit Analysis
  • Costs and Cost Analysis
  • Female
  • Health Maintenance Organizations / economics
  • Humans
  • Income
  • Male
  • Nicotine / administration & dosage
  • Nicotine / therapeutic use*
  • Patient Compliance
  • Self Administration
  • Smoking / economics
  • Smoking Prevention*


  • Chewing Gum
  • Nicotine