The clinical content of preconception care: women with chronic medical conditions

Am J Obstet Gynecol. 2008 Dec;199(6 Suppl 2):S310-27. doi: 10.1016/j.ajog.2008.08.031.


This article reviews the medical conditions that are associated with adverse pregnancy outcomes for women and their offspring. We also present the degree to which specific preconception interventions and treatments can impact the effects of the condition on birth outcomes. Because avoiding, delaying, or achieving optimal timing of a pregnancy is often an important component of the preconception care of women with medical conditions, contraceptive considerations particular to the medical conditions are also presented.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Chronic Disease / therapy*
  • Female
  • Humans
  • Preconception Care*
  • Pregnancy
  • Prenatal Care