Double skeletonized internal thoracic artery vs. double conventional internal thoracic artery in diabetic patients submitted to OPCAB

Rev Bras Cir Cardiovasc. 2008 Jul-Sep;23(3):351-7. doi: 10.1590/s0102-76382008000300011.
[Article in English, Portuguese]

Abstract

Objective: To evaluate the influence of the technique used in the dissection of thoracic arteries in the evolution of diabetic patients submitted to OPCAB.

Methods: Seventy diabetic patients submitted to OPCAB using bilateral thoracic arteries were evaluated. In Group A, thoracic arteries were dissected as a pedicle, while in Group B they were skeletonized.

Results: The mean age of patients in Group A was 52.14 +/- 7.35 years old versus 55.71 +/- 8.1 years for Group B (p=0.057). In Group A, six patients (17.1%) were insulin dependent against nine (25.7%) in Group B (p = 0.561). The EUROSCORE was 3.97 +/- 2.49 for Group A opposed to 4.14 +/- 3.06 for Group B (p = 0.879). The number of distal anastomoses in Group A was 3 +/- 0.77 versus 3.03 +/- 0.89 in Group B (p = 0.981). Three patients (8.57%) from Group A presented with mediastinitis. Insulin dependence was the only significant risk factor (p=0.008) for mediastinitis. In this group the use of skeletonized internal thoracic arteries significantly decreased the incidence of mediastinitis (p = 0.044).

Conclusion: The incidence of mediastinitis was lower in the group for which mammary arteries were dissected using skeletonization. Among insulin-dependent diabetics, 50% of the patients from the group in which the pedicled internal thoracic artery was utilized presented with mediastinitis; the utilization of skeletonized internal thoracic arteries significantly decreases the incidence of mediastinitis.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Brazil / epidemiology
  • Coronary Artery Bypass, Off-Pump*
  • Diabetic Angiopathies / drug therapy
  • Diabetic Angiopathies / surgery*
  • Hemostasis, Surgical / instrumentation
  • Hemostasis, Surgical / methods
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Incidence
  • Insulin / therapeutic use
  • Internal Mammary-Coronary Artery Anastomosis / adverse effects*
  • Internal Mammary-Coronary Artery Anastomosis / methods
  • Internal Mammary-Coronary Artery Anastomosis / mortality
  • Mammary Arteries / transplantation*
  • Mediastinitis / epidemiology*
  • Mediastinitis / etiology
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Tissue and Organ Harvesting / methods*

Substances

  • Hypoglycemic Agents
  • Insulin