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. Nov-Dec 2008;16(6):369-75.
doi: 10.1590/s1678-77572008000600003.

Epidemiological and Oral Manifestations of HIV-positive Patients in a Specialized Service in Brazil

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Free PMC article

Epidemiological and Oral Manifestations of HIV-positive Patients in a Specialized Service in Brazil

Erick Nelo Pedreira et al. J Appl Oral Sci. .
Free PMC article

Abstract

The purpose of this study was to evaluate the prevalence of oral lesions in HIV-positive patients attending the Specialized Service for Infectious-contagious Diseases and Parasitoses of the Health Secretariat of the State of Pará (URE-DIPE/SESPA), in the city of Belém, PA, Brazil. A total of 79 HIV-positive patients (53 males and 26 females) were examined. Clinical and epidemiological evaluations were done by correlating the lesions with gender, race, chronological age, risk behavior and prevailing immune status (CD4+ cells count). Lesion location and the presence of associated factors, such as alcohol use, smoking and denture wearing, were quantified individually for each type of lesion using a diagnostic pattern based on the clinical aspects. Approximately 47% of the patients (n=37) presented some type of oral lesion. Candidiasis (28%) and periodontal disease (28%) were the most common, followed by cervical-facial lymphadenopathy (17.5%). Other lesions observed were hairy leukoplakia, melanin hyperpigmentation, ulcerative stomatitis (aphthous), herpes simplex, frictional keratosis and pyogenic granuloma. This analysis presented some relevance as to the statistical data. Concerning CD4+ cells, most lesions manifested with the reduction of the CD count. There were a larger number of HIV-positive female heterosexual patients. Alcohol and/or smoking were strongly associated with the occurrence of hairy leukoplakia in these patients. Candidiasis and periodontal disease were the most common oro-regional clinical manifestations in the patients.

Figures

FIGURE 1
FIGURE 1. Risk behavior (%) of patients with oral lesions
FIGURE 2
FIGURE 2. Distribution (%) of patients by age
FIGURE 3
FIGURE 3. Predominance (%) of lesions by race
FIGURE 4
FIGURE 4. Distribution (%) of oral lesions according to the aggravating agent

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References

    1. Anil S, Challacombe SJ. Oral lesions of HIV and AIDS in Asia: an overview. Oral Dis. 1997;3(Suppl 1):36–40. - PubMed
    1. Bendick C, Scheifele C, Reichart PA. Oral manifestations in 101 cambodians with HIV and AIDS. J Oral Pathol Med. 2002;31(1):1–4. - PubMed
    1. Carey VJ, Pahwa S, Weinberg A. Reliability of CD4 quantitation in human immunodeficiency virus-positive children: implications for definition of immunologic response to highly active anti retroviral therapy. Clin Diagn Lab Immunol. 2005;12(5):640–643. - PMC - PubMed
    1. Centers for Disease Control (CDC) Persistent, generalized lynphadenopathy among homosexual males. MMWR Morb Mortal Wkl Rep. 1982;31(19):249–251. - PubMed
    1. Chattopadhyay A, Caplan DJ, Slade GD, Shugars DC, Tien HC, Patton LL. Risk indicators for oral candidiasis and oral hair leukoplakia in HIV-infected adults. Community Dent Oral Epidemiol. 2005;33(1):35–44. - PubMed

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