Hyperactivity in boys with attention-deficit/hyperactivity disorder (ADHD): a ubiquitous core symptom or manifestation of working memory deficits?

J Abnorm Child Psychol. 2009 May;37(4):521-34. doi: 10.1007/s10802-008-9287-8.

Abstract

Hyperactivity is currently considered a core and ubiquitous feature of attention-deficit/hyperactivity disorder (ADHD); however, an alternative model challenges this premise and hypothesizes a functional relationship between working memory (WM) and activity level. The current study investigated whether children's activity level is functionally related to WM demands associated with the domain-general central executive and subsidiary storage/rehearsal components using tasks based on Baddeley's (Working memory, thought, and action. New York: Oxford University Press 2007) WM model. Activity level was objectively measured 16 times per second using wrist- and ankle-worn actigraphs while 23 boys between 8 and 12 years of age completed control tasks and visuospatial/phonological WM tasks of increasing memory demands. All children exhibited significantly higher activity rates under all WM relative to control conditions, and children with ADHD (n = 12) moved significantly more than typically developing children (n = 11) under all conditions. Activity level in all children was associated with central executive but not storage/rehearsal functioning, and higher activity rates exhibited by children with ADHD under control conditions were fully attenuated by removing variance directly related to central executive processes.

MeSH terms

  • Attention Deficit Disorder with Hyperactivity / complications*
  • Attention Deficit Disorder with Hyperactivity / physiopathology
  • Attention Deficit Disorder with Hyperactivity / psychology*
  • Child
  • Cognition*
  • Humans
  • Hyperkinesis / physiopathology
  • Hyperkinesis / psychology*
  • Male
  • Memory Disorders / physiopathology
  • Memory Disorders / psychology*
  • Neuropsychological Tests
  • Psychomotor Performance*
  • Reaction Time*
  • Severity of Illness Index
  • Space Perception
  • Task Performance and Analysis
  • Verbal Learning
  • Visual Perception