Genetic Polymorphisms of 16 Y Chromosomal STR Loci in Korean Population

Forensic Sci Int Genet. 2008 Mar;2(2):e9-10. doi: 10.1016/j.fsigen.2007.11.001. Epub 2007 Dec 21.

Abstract

Allele frequencies and haplotypes of 16 Y chromosomal STR loci included in the AmpFlSTR((R)) Yfilertrade mark system were obtained from a sample of 526 unrelated Korean male individuals. A total of 478 haplotypes were observed in the 526 individuals studied, of which 440 were unique. The overall haplotype diversity for the 16 Y-STR loci was 0.9996, and the discrimination capacity was 0.9087. We found 13 atypical alleles, including null, duplicated and microvariant alleles. Microvariants have been characterized by sequencing, 14.1 allele at DYS458 showing the flanking site mutation, 13.1 and 15.2 allele at DYS385a/b showing changes in the repeat structure.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Asian Continental Ancestry Group / genetics*
  • Chromosomes, Human, Y*
  • DNA / genetics
  • DNA / isolation & purification
  • DNA Fingerprinting / methods
  • Gene Frequency
  • Genetic Markers
  • Genotype
  • Haplotypes
  • Humans
  • Korea
  • Male
  • Microsatellite Repeats / genetics*
  • Nucleic Acid Amplification Techniques
  • Polymerase Chain Reaction
  • Polymorphism, Genetic*
  • Population Groups / genetics*
  • Quality Control

Substances

  • Genetic Markers
  • DNA