[Long-term results of iridocyclectomy for iris tumours]

Klin Monbl Augenheilkd. 2008 Dec;225(12):1045-50. doi: 10.1055/s-2008-1027609. Epub 2008 Dec 15.
[Article in German]

Abstract

Background: The aim of this study was to evaluate the long-term survival rate and functional results after iridocyclectomy.

Patients and method: Between 1980 and 2002 39 patients (26 female and 13 male) ranging in age from 20 to 79 years (median m = 58 years) underwent iridocyclectomy for a tumour of periphery iris by means of a lamellar technique or by trepanating. Follow-up time ranged from 3 months to 24 years (m = 11.2 years).

Results: In 21 cases (54 %) there was a malignant tumour including 20 melanomas (mostly spindle-cell and mixed-cell melanomas) and one filiae of a bronchial carcinoma. There was a variety of histopathological entities in the 18 benign lesions (46 %). Naevi were the most frequent. The outcome was satisfactory: 57 % of the patients kept a visual acuity of > 0.5. Three eyes had to be enucleated. The rate of recurrence was 10 % (4 cases). The Kaplan-Meyer estimate for the 10-year-survival of the patients with a malignant iris tumour was 77 %. Two patients died of metastic melanoma following spindle-cell and mixed-cell melanoma.

Conclusion: The long-term functional results after Iridocyclectomy are good, whereas complications and recurrences are rare. The 10-year-survival is high. Over a long period iridocyclectomy is a recommendable surgical procedure for removal of progredient tumours of the anterior uvea.

Publication types

  • Clinical Trial
  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Disease-Free Survival
  • Female
  • Humans
  • Iridectomy / mortality*
  • Iridectomy / statistics & numerical data
  • Iris Neoplasms / mortality*
  • Iris Neoplasms / surgery*
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Prevalence
  • Survival Analysis
  • Survival Rate
  • Treatment Outcome