[Relationship between antioxidant activities and contents of active ingredients in Radix Scutellaria]

Zhongguo Zhong Yao Za Zhi. 2008 Aug;33(16):2019-22.
[Article in Chinese]

Abstract

Objective: To study the relationship between the antioxidant activities and the contents of active ingredients in Radix Scutellaria.

Method: The antioxidant activities of extracts and active ingredients of Radix Scutellaria in NADPH-dependent lipid peroxidation in rat liver microsome were assayed.

Result: Extracts of Radix Scutellaria showed a 50% inhibition of lipid peroxidation in the concentration range of 2.72-18.27 mg x L(-1).

Conclusion: The antioxidant activities of extracts of Radix Scutellaria are not only related with the contents but also the ratio of the active ingredients.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Antioxidants / chemistry
  • Antioxidants / pharmacology*
  • Drugs, Chinese Herbal / pharmacology*
  • Lipid Peroxidation / drug effects
  • Microsomes, Liver / drug effects*
  • Microsomes, Liver / metabolism
  • Rats
  • Rats, Wistar
  • Scutellaria / chemistry*

Substances

  • Antioxidants
  • Drugs, Chinese Herbal