Clinical management for epidermolysis bullosa dystrophica

J Appl Oral Sci. Jan-Feb 2008;16(1):81-5. doi: 10.1590/s1678-77572008000100016.

Abstract

Epidermolysis bullosa (EB) consists of a group of genetic hereditary disorders in which patients frequently present fragile skin and mucosa that form blisters following minor trauma. More than 20 subtypes of EB have been recognized in the literature. Specific genetic mutations are well characterized for most the different EB subtypes and variants. The most common oral manifestations of EB are painful blisters affecting all the oral surfaces. Dental treatment for patients with EB consists of palliative therapy for its oral manifestations along with typical restorative and periodontal procedures. The aim of this article is to describe two dental clinical treatments of recessive dystrophic EB cases and their specific clinical manifestations. The psychological intervention required during the dental treatment of these patients is also presented.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Infective Agents, Local / therapeutic use
  • Blister / psychology
  • Blister / therapy
  • Child, Preschool
  • Chlorhexidine / therapeutic use
  • Dental Plaque / therapy
  • Dental Restoration, Permanent
  • Epidermolysis Bullosa Dystrophica / psychology
  • Epidermolysis Bullosa Dystrophica / therapy*
  • Female
  • Follow-Up Studies
  • Gingivitis / therapy
  • Humans
  • Jaw, Edentulous, Partially / rehabilitation
  • Male
  • Mouth Diseases / psychology
  • Mouth Diseases / therapy*
  • Oral Ulcer / therapy
  • Palliative Care
  • Patient Care Planning
  • Periodontal Diseases / psychology
  • Periodontal Diseases / therapy
  • Radiography, Panoramic
  • Tooth Extraction
  • Toothbrushing

Substances

  • Anti-Infective Agents, Local
  • Chlorhexidine