NK cells in HIV-1 infection: evidence for their role in the control of HIV-1 infection

J Intern Med. 2009 Jan;265(1):29-42. doi: 10.1111/j.1365-2796.2008.02045.x.


Increasing evidence supports the notion that the innate immune response, and in particular, natural killer cells play a central role in determining the quality of the host immune response to infection. In this review we highlight recent evidence that suggests that NK cells influence the clinical fate of HIV-infected individuals.

Publication types

  • Review

MeSH terms

  • CD8-Positive T-Lymphocytes / immunology
  • Female
  • Genetic Predisposition to Disease
  • Genotype
  • HIV Infections / immunology*
  • HIV-1 / physiology*
  • Histocompatibility Antigens Class I / immunology
  • Humans
  • Immunity, Cellular
  • Killer Cells, Natural / physiology*
  • Male
  • Receptors, KIR / immunology


  • Histocompatibility Antigens Class I
  • Receptors, KIR