Stereoselective macrocyclization through zirconocene-mediated coupling of achiral dialkynes

John F Tannaci; Ian H Kratter; Eric A Rider; Jennifer L McBee; Adam D Miller; T Don Tilley

doi:10.1039/b815750b

Stereoselective macrocyclization through zirconocene-mediated coupling of achiral dialkynes

Chem Commun (Camb). 2009 Jan 8:(2):233-4. doi: 10.1039/b815750b. Epub 2008 Nov 26.

Authors

John F Tannaci¹, Ian H Kratter, Eric A Rider, Jennifer L McBee, Adam D Miller, T Don Tilley

Affiliation

¹ Department of Chemistry, University of California, Berkeley, California, 94720-1460, USA.

PMID: 19099079
DOI: 10.1039/b815750b

Abstract

1,4-Bis[trimethylsilyl(ethynyl)]naphthalene () and 1,4-bis[trimethylsilyl(ethynyl)]anthracene () undergo diastereoselective coupling with Cp2Zr(py)(Me3SiC[triple bond, length as m-dash]CSiMe3) to give trimeric macrocycles in good yield.