Multidrug efflux transporters in the MATE family

Teruo Kuroda; Tomofusa Tsuchiya

doi:10.1016/j.bbapap.2008.11.012

Multidrug efflux transporters in the MATE family

Biochim Biophys Acta. 2009 May;1794(5):763-8. doi: 10.1016/j.bbapap.2008.11.012. Epub 2008 Dec 6.

Authors

Teruo Kuroda¹, Tomofusa Tsuchiya

Affiliation

¹ Department of Genome Applied Microbiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700-8530, Japan.

PMID: 19100867
DOI: 10.1016/j.bbapap.2008.11.012

Abstract

The MATE (Multidrug And Toxic Compound Extrusion) family is the most recently categorized one among five multidrug efflux transporter families. As far as we know, about twenty MATE transporters have been characterized so far. According to the information in sequence databases, huge numbers of MATE transporters seem to be present in various microorganisms. In this review, we would like to summarize the properties of the MATE-family transporters.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Antiporters / genetics
Antiporters / physiology
Bacterial Proteins / genetics
Bacterial Proteins / physiology
Membrane Transport Proteins / genetics
Membrane Transport Proteins / physiology*
Organic Cation Transport Proteins / physiology*
Phylogeny
Salmonella typhimurium / genetics
Salmonella typhimurium / pathogenicity
Substrate Specificity
Virulence

Substances

Antiporters
Bacterial Proteins
Membrane Transport Proteins
NorM protein, bacteria
Organic Cation Transport Proteins