Multidrug efflux transporters in the MATE family

Biochim Biophys Acta. 2009 May;1794(5):763-8. doi: 10.1016/j.bbapap.2008.11.012. Epub 2008 Dec 6.


The MATE (Multidrug And Toxic Compound Extrusion) family is the most recently categorized one among five multidrug efflux transporter families. As far as we know, about twenty MATE transporters have been characterized so far. According to the information in sequence databases, huge numbers of MATE transporters seem to be present in various microorganisms. In this review, we would like to summarize the properties of the MATE-family transporters.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antiporters / genetics
  • Antiporters / physiology
  • Bacterial Proteins / genetics
  • Bacterial Proteins / physiology
  • Membrane Transport Proteins / genetics
  • Membrane Transport Proteins / physiology*
  • Organic Cation Transport Proteins / physiology*
  • Phylogeny
  • Salmonella typhimurium / genetics
  • Salmonella typhimurium / pathogenicity
  • Substrate Specificity
  • Virulence


  • Antiporters
  • Bacterial Proteins
  • Membrane Transport Proteins
  • NorM protein, bacteria
  • Organic Cation Transport Proteins