Antibiotic resistance in urinary isolates of Escherichia coli from college women with urinary tract infections

Antimicrob Agents Chemother. 2009 Mar;53(3):1285-6. doi: 10.1128/AAC.01188-08. Epub 2008 Dec 22.

Abstract

Of 176 urine isolates from female students positive for Escherichia coli, 29.6% were trimethoprim-sulfamethoxazole resistant and none were nitrofurantoin resistant. Among students with a history of urinary tract infection (UTI) (n = 119), resistance to ciprofloxacin was 11.8%, compared to 1.8% among those without prior UTI. Nitrofurantoin should be considered for empirical therapy of lower tract UTI.

MeSH terms

  • Adolescent
  • Adult
  • Ciprofloxacin / pharmacology
  • Ciprofloxacin / therapeutic use
  • Drug Resistance, Microbial*
  • Escherichia coli / drug effects*
  • Escherichia coli / isolation & purification
  • Female
  • Humans
  • Nitrofurantoin / pharmacology
  • Nitrofurantoin / therapeutic use
  • Trimethoprim, Sulfamethoxazole Drug Combination / pharmacology
  • Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
  • Urinary Tract Infections / drug therapy*
  • Urinary Tract Infections / genetics
  • Young Adult

Substances

  • Ciprofloxacin
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Nitrofurantoin