Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer

Anticancer Drugs. 2009 Mar;20(3):215-6. doi: 10.1097/CAD.0b013e3283163c26.

Abstract

Castration-resistant prostate cancer (CRPC) is an incurable disease with limited treatment options. Herbal supplements are unconventional treatments for a variety of diseases. Active hemicellulose compound (AHCC) is a Japanese supplement discovered by hybridizing several mushrooms used in traditional healing for the purpose of maintaining 'super immunity'. We report on a 66-year-old gentleman with CRPC with an excellent serologic response to AHCC. This case hypothesizes that AHCC may have potential activity against CRPC.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / blood
  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / radiotherapy
  • Adenocarcinoma / secondary*
  • Anilides / administration & dosage
  • Anilides / pharmacology
  • Animals
  • Antineoplastic Agents, Hormonal / pharmacology
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Basidiomycota
  • Combined Modality Therapy
  • Drug Resistance, Neoplasm
  • Humans
  • Leuprolide / administration & dosage
  • Leuprolide / pharmacology
  • Lumbar Vertebrae*
  • Male
  • Nitriles / administration & dosage
  • Nitriles / pharmacology
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / therapeutic use*
  • Polysaccharides / administration & dosage
  • Polysaccharides / therapeutic use*
  • Prostate-Specific Antigen / blood*
  • Prostatic Neoplasms / blood
  • Prostatic Neoplasms / drug therapy*
  • Radioisotopes / therapeutic use
  • Remission Induction
  • Samarium / therapeutic use
  • Self Medication
  • Spinal Neoplasms / blood
  • Spinal Neoplasms / drug therapy
  • Spinal Neoplasms / radiotherapy
  • Spinal Neoplasms / secondary*
  • Tosyl Compounds / administration & dosage
  • Tosyl Compounds / pharmacology

Substances

  • Anilides
  • Antineoplastic Agents, Hormonal
  • Nitriles
  • Plant Extracts
  • Polysaccharides
  • Radioisotopes
  • Tosyl Compounds
  • Samarium
  • bicalutamide
  • Prostate-Specific Antigen
  • Leuprolide
  • Active Hexose Correlated Compound