Zinc-catalyzed nucleophilic substitution reaction of chlorosilanes with organomagnesium reagents

Kei Murakami; Hideki Yorimitsu; Koichiro Oshima

doi:10.1021/jo802433t

Zinc-catalyzed nucleophilic substitution reaction of chlorosilanes with organomagnesium reagents

J Org Chem. 2009 Feb 6;74(3):1415-7. doi: 10.1021/jo802433t.

Authors

Kei Murakami¹, Hideki Yorimitsu, Koichiro Oshima

Affiliation

¹ Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

PMID: 19108632
DOI: 10.1021/jo802433t

Abstract

Zinc-catalyzed nucleophilic substitution reactions of chlorosilanes with organomagnesium reagents afford various tetraorganosilanes under mild reaction conditions. The reactions can be performed on large scale and allow efficient preparation of functionalized tetraorganosilanes.