Self-reported Stroke and Myocardial Infarction Had Adequate Sensitivity in a Population-Based Prospective Study JPHC (Japan Public Health Center)-based Prospective Study

J Clin Epidemiol. 2009 Jun;62(6):667-73. doi: 10.1016/j.jclinepi.2008.07.016. Epub 2008 Dec 23.


Objective: We sought to clarify the validity of self-reported stroke and myocardial infarction (MI) among Japanese population, because information on the validity, particularly on the sensitivity, of self-reported cardiovascular disease is limited and may differ among countries.

Study design and setting: Using the 10-year follow-up questionnaire and a stroke and MI registry in the Japan Public Health Center-based prospective Study (JPHC Study) cohort (n=91,186), we calculated sensitivity and positive predictive values of self-reported stroke and MI incidence over 10 years.

Results: Sensitivity of self-reported incident stroke was 73%, and that for MI was 82%. Positive predictive values were 57% for stroke and 43% for MI. The supplemental inclusion of self-reported angina pectoris increased the sensitivity of MI to 89%, but attenuated the positive predictive value to 18%. Sensitivity of self-reported stroke was highest for subarachnoid hemorrhage (88%), but did not differ greatly among other stroke subtypes, affected sites or size.

Conclusion: Self-reported stroke and MI seem sensitive enough to use for exclusion of stroke and MI at baseline in Japanese cohort studies. However, self-report has too many false positives to be used as the only criterion for incident stroke and MI.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Angina Pectoris / epidemiology
  • Data Collection
  • Female
  • Humans
  • Japan / epidemiology
  • Male
  • Middle Aged
  • Myocardial Infarction / epidemiology*
  • Prospective Studies
  • Risk Factors
  • Self Disclosure
  • Sensitivity and Specificity
  • Stroke / epidemiology*
  • Subarachnoid Hemorrhage / epidemiology
  • Surveys and Questionnaires