Endometrial mesenchymal stem cells isolated from the menstrual blood

Bull Exp Biol Med. 2008 Apr;145(4):539-43. doi: 10.1007/s10517-008-0136-0.

Abstract

Stem cells from the endometrium isolated during menstrual bleeding were characterized. By their main surface markers, differentiation potential, and morphological signs these cells belong to mesenchymal stem cells. Specific features of this cell type are high clonogenic activity and low capacity to adipocyte differentiation.

MeSH terms

  • Adipogenesis / physiology
  • Adult
  • Antigens, CD / metabolism
  • Blood Cells / cytology
  • Blood Cells / metabolism
  • Cell Differentiation / physiology
  • Cell Separation / methods
  • Cells, Cultured
  • Endoglin
  • Endometrium / cytology*
  • Endometrium / metabolism
  • Female
  • Humans
  • Hyaluronan Receptors / metabolism
  • Menstruation / blood*
  • Mesenchymal Stem Cells / cytology*
  • Mesenchymal Stem Cells / metabolism
  • Mesenchymal Stem Cells / physiology
  • Middle Aged
  • Osteogenesis / physiology
  • Receptors, Cell Surface / metabolism
  • Thy-1 Antigens / metabolism
  • Young Adult

Substances

  • Antigens, CD
  • CD44 protein, human
  • ENG protein, human
  • Endoglin
  • Hyaluronan Receptors
  • Receptors, Cell Surface
  • Thy-1 Antigens