Persistent vancomycin and high-level gentamicin-resistant Enterococcus faecium bacteremia and intra-aortic thrombus in an extremely low birth-weight infant

J Perinatol. 2009 Jan;29(1):66-8. doi: 10.1038/jp.2008.137.

Abstract

Vancomycin-resistant Enterococcus (VRE) sepsis is emerging as a significant problem in the intensive care setting. The treatment at any age is challenging, but there is a dearth of information on this infection and its treatment in the very premature infant. We describe successful treatment of persistent bacteremia caused by Enterococcus faecium with vancomycin and high-level gentamicin resistance in a 10-day-old former 23-week premature male infant.

Publication types

  • Case Reports

MeSH terms

  • Aortic Diseases / drug therapy
  • Aortic Diseases / microbiology*
  • Bacteremia / complications
  • Bacteremia / drug therapy
  • Diseases in Twins
  • Drug Resistance, Multiple, Bacterial
  • Enterococcus faecium / isolation & purification*
  • Fatal Outcome
  • Gentamicins / therapeutic use*
  • Gestational Age
  • Gram-Positive Bacterial Infections / complications
  • Gram-Positive Bacterial Infections / drug therapy*
  • Humans
  • Infant, Extremely Low Birth Weight
  • Infant, Newborn
  • Male
  • Thrombosis / drug therapy
  • Thrombosis / microbiology*
  • Vancomycin / therapeutic use*

Substances

  • Gentamicins
  • Vancomycin