Use of intradermal botulinum toxin to reduce sebum production and facial pore size

J Drugs Dermatol. 2008 Sep;7(9):847-50.

Abstract

Objective: Review the safety profile and subjective efficacy of intradermal botulinum toxin type A in facial pore size and sebum production.

Design: Retrospective analysis of 20 patients.

Results: Twenty consecutive patients with a single application of intradermal botulinum toxin type A were examined: Patients (17/20) noted an improvement in sebum production and a decrease in pores size at 1 month after injection. No complications were observed, and 17/20 patients were satisfied with the procedure.

Conclusion: Preliminary data suggests that intradermal botulinum toxin may play a role in decreasing sebum production. Further quantitive study may be necessary to determine effects of intradermal botulinum toxin on pore size.

MeSH terms

  • Botulinum Toxins, Type A / administration & dosage
  • Botulinum Toxins, Type A / pharmacology*
  • Face
  • Follow-Up Studies
  • Humans
  • Injections, Intradermal
  • Neuromuscular Agents / administration & dosage
  • Neuromuscular Agents / pharmacology*
  • Porosity
  • Retrospective Studies
  • Sebum / drug effects*
  • Skin / anatomy & histology
  • Skin / drug effects*
  • Skin / metabolism

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A