Bifunctional dendrimers: from robust synthesis and accelerated one-pot postfunctionalization strategy to potential applications

Angew Chem Int Ed Engl. 2009;48(12):2126-30. doi: 10.1002/anie.200804987.


A fourth wheel: Two sets of bifunctional AB(2)C dendrimers having internal acetylene/azides and external hydroxy groups were constructed utilizing benign synthetic protocols. An in situ postfunctionalization strategy was successfully carried out to illustrate the chemoselective nature of these dendrimers. The dendrimers were also transformed into dendritic nanoparticles or utilized as dendritic crosslinkers for the fabrication hydrogels.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylene / chemistry
  • Azides / chemistry
  • Dendrimers / chemical synthesis*
  • Dendrimers / chemistry
  • Dendrimers / radiation effects
  • Hydrogels / chemistry
  • Nanoparticles / chemistry
  • Ultraviolet Rays


  • Azides
  • Dendrimers
  • Hydrogels
  • Acetylene