Abstract
Diastereoselective aldol reactions of enolates of alpha-hydroxy ester with different aldehydes are metal tunable, providing either anti- or syn- products. The highest anti-selectivities were obtained with TiCl(OiPr)(3), while Ti(OiPr)(4) provides the opposite syn-products.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alcohols / chemistry*
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Aldehydes / chemistry*
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Chelating Agents / chemistry
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Glycolates / chemistry*
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Organometallic Compounds / chemistry*
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Stereoisomerism
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Substrate Specificity
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Titanium / chemistry*
Substances
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Alcohols
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Aldehydes
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Chelating Agents
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Glycolates
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Organometallic Compounds
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glycolic acid
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Titanium