Comparison of SF-36 and WHOQOL-100 in patients with stroke

Neurol India. 2008 Oct-Dec;56(4):426-32. doi: 10.4103/0028-3886.44573.


Background and aims: Two widely used evaluation tools for the quality of life are the 36-item Short-Form Health Survey (SF-36) and World Health Organization Quality of Life Assessment (100-item version) (WHOQOL-100), however, these tools have not been compared for patients with stroke to date. The specific objectives of this study were: 1) to study the effect of stroke on quality of life (QOL) as measured by the SF-36 and by the WHOQOL-100, and 2) to compare these two instruments.

Settings and design: Seventy patients who were admitted to the neurology clinic six months after stroke were included in this study.

Patients and methods: As a data-collecting device, the SF-36 and WHOQOL-100 scales were used. An additional questionnaire was administered to obtain demographic data.

Statistical analysis: Pearson correlation analysis was performed and Blant-Altman Plots were used. Psychometric analysis was performed.

Results: In stroke, the most flustered domains of quality of life were vitality and general health perception fields in the SF-36 and in the WHOQL-100, independence level field, overall QOL and general health perceptions. While there was a fair degree of relationship (r= 0.25-0.50) between general health perceptions, physical, social and mental fields that were similar fields of scales, a fair and moderate to good relationship was found between different fields. Limits of agreement in similar domains of the two instruments were very large. In all four demonstrated Bland-Altman plots, there was agreement of the scales in the measurements of similar fields of quality of life.

Conclusion: This study demonstrated that both the SF-36 and WHOQOL-100 quality of life scales are useful in the practical evaluation of patients with stroke.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Male
  • Middle Aged
  • Quality of Life*
  • Reproducibility of Results
  • Stroke / psychology*
  • Surveys and Questionnaires*
  • Young Adult