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, 14 (1), 174-90

Coordination Modes of a Schiff Base Pentadentate Derivative of 4-aminoantipyrine With cobalt(II), nickel(II) and copper(II) Metal Ions: Synthesis, Spectroscopic and Antimicrobial Studies

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Coordination Modes of a Schiff Base Pentadentate Derivative of 4-aminoantipyrine With cobalt(II), nickel(II) and copper(II) Metal Ions: Synthesis, Spectroscopic and Antimicrobial Studies

Sulekh Chandra et al. Molecules.

Abstract

Transition metal complexes of Co(II), Ni(II) and Cu(II) metal ions with general stoichiometry [M(L)X]X and [M(L)SO(4)], where M = Co(II), Ni(II) and Cu(II), L = 3,3'-thiodipropionic acid bis(4-amino-5-ethylimino-2,3-dimethyl-1-phenyl-3-pyrazoline) and X = NO(3)(-), Cl(-) and OAc(-), have been synthesized and structurally characterized by elemental analyses, molar conductance measurements, magnetic susceptibility measurements and spectral techniques like IR, UV and EPR. The nickel(II) complexes were found to have octahedral geometry, whereas cobalt(II) and copper(II) complexes were of tetragonal geometry. The covalency factor (beta) and orbital reduction factor (k) suggest the covalent nature of the complexes. The ligand and its complexes have been screened for their antifungal and antibacterial activities against three fungi, i.e. Alternaria brassicae, Aspergillus niger and Fusarium oxysporum and two bacteria, i.e. Xanthomonas compestris and Pseudomonas aeruginosa.

Figures

Scheme 1
Scheme 1
Synthesis of ligand.
Figure 1
Figure 1
Mass spectrum of the ligand L.
Figure 2
Figure 2
1H-NMR spectrum of the ligand L.
Figure 3
Figure 3
13C-NMR spectrum of the ligand L.
Figure 4
Figure 4
EPR spectrum of the [Cu(L)Cl]Cl complex.
Figure 5
Figure 5
Structure of complexes (a) [M(L)X]X, (b) [M(L)SO4], where M =Co(II), Ni(II) and Cu(II), L = ligand and X = NO3, Cl and OAc.
Figure 6
Figure 6
Antifungal activity against Fusarium oxysporum of: (A) ligand; (B) [Ni(L)NO3]NO3; (C) [Co(L)Cl]Cl and (D) [Cu(L)NO3]NO3.

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