Y-chromosome variability in four Native American populations from Panama

Hum Biol. 2008 Jun;80(3):287-302. doi: 10.3378/1534-6617-80.3.287.


The allele and haplotype frequencies for 13 Y-chromosome short tandem repeats (STRs) [nine STR loci of the minimal Y-chromosome haplotype (DYS19 - DYS385a - DYS385b - DYS389I - DYS389II - DYS390 - DYS391- DYS392 - DYS393) plus four additional loci (DYS388, DYS426, DYS439, DXYS156)] were determined in 99 males from 4 Panamanian native American populations, including the Chibcha-speaking Ngöbé and Kuna and the Chocó-speaking Emberá and Wounan. Fifty haplotypes were identified, of which 48 (96%) were specific to a single population and 29 (63%) were found in only a single individual. Gene diversity per locus per population ranged from 0 to 0.814, with the highest gene diversity present at the DYS389II locus in the Emberá. The haplotypic discrimination capacity was low, ranging from 42.3% in the Kuna to 63.1% in the Wounan. The four tribes showed a high degree of differentiation both at the Y chromosome and in the mitochondrial genome, highlighting the importance of genetic structure even in geographically proximate and linguistically related populations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Analysis of Variance
  • Chromosomes, Human, Y / genetics*
  • Gene Flow / genetics*
  • Genetic Variation / genetics*
  • Haplotypes
  • Humans
  • Indians, North American / statistics & numerical data*
  • Male
  • Microsatellite Repeats
  • Panama
  • Pilot Projects
  • United States