[Platelets: biochemistry and physiology]

Hamostaseologie. 2008 Dec;28(5):289-98.
[Article in German]

Abstract

This article reviews the roles of blood platelets in haemostasis as well as in the pathogenesis of thromboembolic diseases. Besides the basic processes in primary haemostasis, platelet adhesion, platelet secretion, platelet aggregation, clot retraction, the new model of thrombin formation on the platelet surface is presented. The different signal transduction pathways in platelets are a main focus of this review.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Blood Platelets / cytology
  • Blood Platelets / metabolism
  • Blood Platelets / physiology*
  • Endothelium, Vascular / physiology
  • Fibrin / physiology
  • Fibrinogen / physiology
  • Hemostasis / physiology*
  • Humans
  • Platelet Adhesiveness
  • Platelet Aggregation
  • Signal Transduction
  • Thrombin / metabolism
  • Thromboembolism / blood*
  • von Willebrand Factor / physiology

Substances

  • von Willebrand Factor
  • Fibrin
  • Fibrinogen
  • Thrombin