Light in aminocatalysis: the asymmetric intermolecular alpha-alkylation of aldehydes

Angew Chem Int Ed Engl. 2009;48(8):1360-3. doi: 10.1002/anie.200804995.


Following the light: Photoredox catalysis along with aminocatalysis have proved to be the right combination for one of the most challenging asymmetric transformation in organic synthesis: the direct intermolecular alpha-alkylation of aldehydes.