Real-time PCR and subsequent pyrosequencing for screening of penA mosaic alleles and prediction of reduced susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae

APMIS. 2008 Nov;116(11):1004-8. doi: 10.1111/j.1600-0463.2008.01062.x.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Anti-Bacterial Agents / pharmacology*
  • Base Sequence
  • Cephalosporins / pharmacology*
  • Drug Resistance, Bacterial / genetics*
  • Genes, Bacterial / genetics
  • Gonorrhea / microbiology
  • Humans
  • Molecular Sequence Data
  • Neisseria gonorrhoeae / drug effects
  • Neisseria gonorrhoeae / genetics
  • Neisseria gonorrhoeae / isolation & purification*
  • Penicillin-Binding Proteins / genetics*
  • Polymerase Chain Reaction / methods*
  • Sequence Alignment
  • Sequence Analysis, DNA / methods*

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • Penicillin-Binding Proteins