A chromatic explosion: the development and future of multiparameter flow cytometry

Immunology. 2008 Dec;125(4):441-9. doi: 10.1111/j.1365-2567.2008.02989.x.


Multiparameter flow cytometry has matured tremendously since the 1990s, giving rise to a technology that allows us to study the immune system in unprecedented detail. In this article, we review the development of hardware, reagents, and data analysis tools for multiparameter flow cytometry and discuss future advances in the field. Finally, we highlight new applications that use this technology to reveal previously unappreciated aspects of cell biology and immunity.

Publication types

  • Review

MeSH terms

  • Animals
  • Coloring Agents
  • Equipment Design
  • Flow Cytometry / methods*
  • Flow Cytometry / trends
  • Forecasting
  • Humans
  • Immune System Diseases / diagnosis
  • Statistics as Topic*


  • Coloring Agents