Dental implants have been widely used clinically, but there still remain great challenges for a stronger bone-implant bonding and a shorter rehabilitation time. Osseointegration of dental implant is crucial for their long term clinical success. Recently, there are abundant evidences showing that low mechanical stimuli can strengthen bones, inhibit osteopenia and enhance bone healing. It has been showed that low-amplitude mechanical stimuli have favorable influence on osteoblasts and their precursors. Preliminary studies indicated that low-magnitude mechanical stimuli may assist in implant osseointegration. So collectively we hypothesize that low-magnitude mechanical vibration may be applied clinically to strengthen and accelerate osseointegration of dental implants.