Sinus Grafting Using Autogenous Bone and Platelet-Rich Plasma: Histologic Outcomes in Humans

Int J Periodontics Restorative Dent. 2008 Dec;28(6):585-91.

Abstract

Four partially edentulous patients received particulate autogenous bone and platelet-rich plasma (PRP) in one sinus and particulate autogenous bone alone in the contralateral sinus. After 6 months of healing, two or three Osseotite implants were inserted, and an additional Osseotite mini-implant was placed into the graft through the lateral wall of the sinus. At abutment connection, the mini-implants were retrieved for histologic examination. Despite similar clinical and radiographic healing patterns, a higher bone-to-implant contact rate was observed on the implants placed in bone and PRP than on those placed in bone only (46.75% +/- 13.6% versus 20.5% +/- 5.57%, respectively).

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Alveolar Bone Loss / surgery
  • Alveolar Process / pathology
  • Alveolar Ridge Augmentation / methods*
  • Bone Regeneration / physiology
  • Bone Transplantation / methods*
  • Dental Abutments
  • Dental Implants
  • Female
  • Follow-Up Studies
  • Humans
  • Jaw, Edentulous, Partially / rehabilitation
  • Jaw, Edentulous, Partially / surgery
  • Male
  • Maxilla / pathology
  • Maxilla / surgery*
  • Maxillary Sinus / pathology
  • Maxillary Sinus / surgery*
  • Middle Aged
  • Osseointegration / physiology
  • Platelet-Rich Plasma*
  • Surface Properties
  • Treatment Outcome

Substances

  • Dental Implants