Synthesis and antimicrobial activity of ciprofloxacin and norfloxacin permanently bonded to polyethylene glycol by a thiourea linker

J Antibiot (Tokyo). 2009 Feb;62(2):113-6. doi: 10.1038/ja.2008.26. Epub 2009 Jan 16.

Authors

Gábor Pintér¹, Pál Horváth, Sándor Bujdosó, Ferenc Sztaricskai, Sándor Kéki, Miklós Zsuga, Szilvia Kardos, Ferenc Rozgonyi, Pál Herczegh

Affiliation

¹ Department of Pharmaceutial Chemistry, University of Debrecen, Debrecen, Hungary.

PMID: 19148205
DOI: 10.1038/ja.2008.26

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemical synthesis*
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects*
Ciprofloxacin / chemical synthesis*
Ciprofloxacin / pharmacology*
Cross-Linking Reagents
Indicators and Reagents
Mass Spectrometry
Microbial Sensitivity Tests
Norfloxacin / chemical synthesis*
Norfloxacin / pharmacology*
Polyethylene Glycols / chemistry*
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Spectrophotometry, Ultraviolet
Thiourea / chemistry*

Substances

Anti-Bacterial Agents
Cross-Linking Reagents
Indicators and Reagents
Polyethylene Glycols
Ciprofloxacin
Thiourea
Norfloxacin