Brief report: on the concordance percentages for Autistic Spectrum Disorder of twins

J Autism Dev Disord. 2009 May;39(5):806-8. doi: 10.1007/s10803-008-0683-2. Epub 2009 Jan 16.


In the development of genetic theories of Autistic Spectrum Disorder (ASD) various characteristics of monozygotic (MZ) and dizygotic (DZ) twins are often considered. This paper sets forth a possible refinement in the interpretation of the MZ twin concordance percentages for ASD underlying such genetic theories, and, drawing the consequences from that refinement, a possible early environmental factor in the later development of ASD.

MeSH terms

  • Autistic Disorder / genetics*
  • Child
  • Diseases in Twins / genetics*
  • Humans
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Twins, Dizygotic / genetics
  • Twins, Monozygotic / genetics