Future risk of diabetes in mother and child after gestational diabetes mellitus

Int J Gynaecol Obstet. 2009 Mar:104 Suppl 1:S25-6. doi: 10.1016/j.ijgo.2008.11.025. Epub 2009 Jan 15.


Gestational diabetes mellitus (GDM) is a common pregnancy complication with increased maternal and perinatal morbidity. However, significant long-term morbidity also exists for the mother and offspring. Women with previous GDM have a very high risk of developing overt diabetes, primarily type 2 diabetes, later in life. Moreover, the risk of the metabolic syndrome is increased 3-fold in these women. Their offspring have an 8-fold risk of diabetes/prediabetes at 19-27 years of age. Thus, GDM is part of a vicious circle which increases the development of diabetes in the coming generations.

MeSH terms

  • Adult
  • Animals
  • Diabetes Mellitus, Type 1 / epidemiology
  • Diabetes Mellitus, Type 1 / etiology
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / etiology*
  • Diabetes, Gestational / epidemiology
  • Diabetes, Gestational / physiopathology*
  • Female
  • Humans
  • Hyperglycemia / complications
  • Metabolic Syndrome / epidemiology
  • Metabolic Syndrome / etiology
  • Prediabetic State / epidemiology
  • Prediabetic State / etiology
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Risk Factors
  • Young Adult