Propagation of a Brazilian isolate of Anaplasma marginale with appendage in a tick cell line (BME26) derived from Rhipicephalus (Boophilus) microplus

Vet Parasitol. 2009 Apr 6;161(1-2):150-3. doi: 10.1016/j.vetpar.2008.12.006. Epub 2008 Dec 13.


Anaplasma marginale is a tick-borne pathogen of cattle responsible for the disease anaplasmosis. Data suggest that Rhipicephalus (Boophilus) microplus and R. annulatus may be the major tick vectors of A. marginale in tropical and subtropical regions of the world. In this work we demonstrated the first infection and propagation of a Brazilian isolate of A. marginale (UFMG1) in the BME26 cell line derived originally from embryos of R. (Boophilus) microplus. The establishment of A. marginale infection in a cell line derived from R. (Boophilus) microplus is relevant for studying the A. marginale/tick interface.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anaplasma marginale / physiology*
  • Animals
  • Brazil
  • Cell Culture Techniques
  • Cell Line
  • Rhipicephalus / cytology*